We found that the model has low statistical power when inbreeding depression is caused by the build-up of mildly deleterious alleles. [4] For example, the ABO blood grouping is controlled by the ABO gene, which has six common alleles. 'max': 36, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_rightslot' }}, { bidder: 'onemobile', params: { dcn: '8a969411017171829a5c82bb4deb000b', pos: '8a9691010178783c4831416439820259' }}, { bidder: 'ix', params: { siteId: '194852', size: [300, 250] }}, storage: { {code: 'ad_rightslot2', pubstack: { adUnitName: 'cdo_rightslot2', adUnitPath: '/23202586/cdo_rightslot2' }, mediaTypes: { banner: { sizes: [[300, 250], [120, 600], [160, 600]] } }, Any opinions in the examples do not represent the opinion of the Cambridge Dictionary editors or of Cambridge University Press or its licensors. {code: 'ad_leftslot', pubstack: { adUnitName: 'cdo_leftslot', adUnitPath: '/23202586/cdo_leftslot' }, mediaTypes: { banner: { sizes: [[120, 600], [160, 600], [300, 600]] } }, { bidder: 'appnexus', params: { placementId: '11654149' }}, if(!isPlusPopupShown()) iasLog("criterion : cdo_tc = resp"); A notable example of this is Gregor Mendel's discovery that the white and purple flower colors in pea plants were the result of "pure line" traits, that is a single gene with two alleles. expires: 60 { bidder: 'ix', params: { siteId: '555365', size: [300, 250] }}, bids: [{ bidder: 'rubicon', params: { accountId: '17282', siteId: '162036', zoneId: '776156', position: 'atf' }}, { bidder: 'ix', params: { siteId: '195464', size: [300, 600] }}, { bidder: 'appnexus', params: { placementId: '11654149' }}, { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_rightslot' }}]}, { bidder: 'onemobile', params: { dcn: '8a969411017171829a5c82bb4deb000b', pos: '8a9694390178783c4ccf416425e10264' }}, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_btmslot' }}, | Human genetic variation", "The nature of diversity and diversification at the ABO locus", "dbSNP: a database of single nucleotide polymorphisms", "What effect do variants in coding regions have? Übersetzungen. }); document.head.appendChild(btScript); var pbMobileLrSlots = [ Nearly all multicellular organisms have two sets of chromosomes at some point in their life cycle; that is, they are diploid. { bidder: 'appnexus', params: { placementId: '11653860' }}, partner: "uarus31" { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_rightslot2' }}]}]; { bidder: 'ix', params: { siteId: '555365', size: [120, 600] }}, } googletag.pubads().setTargeting("cdo_pt", "entry"); See Amorphic allele, Pseudoallele allele, Reeler allele, Wimp allele. if(refreshConfig.enabled == true) addPrebidAdUnits(pbAdUnits); "loggedIn": false { bidder: 'ix', params: { siteId: '195451', size: [300, 250] }}, // FIXME: (temporary) - send ad requests only if PlusPopup is not shown Webster’s New World College Dictionary, 4th … { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_btmslot' }}]}]; 'buckets': [{ (gene) alelo nm nombre masculino: Sustantivo de género exclusivamente masculino, que lleva los artículos el o un en singular, y los o unos en plural. resistance allele. iframe: { { bidder: 'appnexus', params: { placementId: '11654157' }}, Word Origin. var googletag = googletag || {}; name: "_pubcid", name: "pubCommonId", { bidder: 'onemobile', params: { dcn: '8a9690ab01717182962182bb50ce0007', pos: '8a9699e70178783c43f941652a820248' }}, Bateson, W. and Saunders, E. R. (1902) "The facts of heredity in the light of Mendel’s discovery." filter: 'include' { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_topslot' }}]}, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_leftslot' }}, Learn more. Definition of allele noun in Oxford Advanced American Dictionary. See more. 'min': 0, expires: 365 One of two or more alternative forms of a gene that arise by mutation and are found at the same place on a chromosome. dfpSlots['rightslot2'] = googletag.defineSlot('/23202586/cdo_rightslot2', [[300, 250], [120, 600], [160, 600]], 'ad_rightslot2').defineSizeMapping(mapping_rightslot2).setTargeting('sri', '0').setTargeting('vp', 'mid').setTargeting('hp', 'right').addService(googletag.pubads()); { bidder: 'ix', params: { siteId: '195464', size: [160, 600] }}, An allele is a form of a gene at a particular position on a chromosome.15 It is the bit of coding DNA at that place.p6 Typical plants and animals have two sets of chromosomes, one set inherited from each parent.123 These organisms are called diploid. { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_btmslot' }}, { bidder: 'sovrn', params: { tagid: '446381' }}, In many cases, genotypic interactions between the two alleles at a locus can be described as dominant or recessive, according to which of the two homozygous phenotypes the heterozygote most resembles. } { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_rightslot2' }}]}]; Usage explanations of natural written and spoken English, 0 && stateHdr.searchDesk ? It can also refer to different sequence variations for several-hundred base-pair or more region of the genome that codes for a protein. What is allele? iasLog("criterion : cdo_c = " + ["science_geographic_locales"]); googletag.cmd.push(function() { Lernen Sie die Übersetzung für 'allele' in LEOs Englisch ⇔ Deutsch Wörterbuch. priceGranularity: customGranularity, allele in British English. bidders: '*', { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_topslot' }}, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_btmslot' }}, { bidder: 'ix', params: { siteId: '195466', size: [728, 90] }}, { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_btmslot' }}]}, googletag.pubads().setTargeting('cdo_alc_pr', pl_p.split(",")); bids: [{ bidder: 'rubicon', params: { accountId: '17282', siteId: '162050', zoneId: '776336', position: 'btf' }}, { bidder: 'ix', params: { siteId: '195466', size: [728, 90] }}, { bidder: 'openx', params: { unit: '539971066', delDomain: 'idm-d.openx.net' }}, window.ga=window.ga||function(){(ga.q=ga.q||[]).push(arguments)};ga.l=+new Date; { bidder: 'onemobile', params: { dcn: '8a969411017171829a5c82bb4deb000b', pos: '8a9699e70178783c43f941643ca4022f' }}, bids: [{ bidder: 'rubicon', params: { accountId: '17282', siteId: '162036', zoneId: '776160', position: 'atf' }}, { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_topslot' }}]}, An allele is one of a pair of genes that appear at a particular location on a particular chromosome and control the same characteristic, such as blood type or color … Each of two or more alternative forms of a gene that arise by mutation and are found at the same place on a chromosome. 'cap': true { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_MidArticle' }}, window.__tcfapi('removeEventListener', 2, function(success){ bids: [{ bidder: 'rubicon', params: { accountId: '17282', siteId: '162036', zoneId: '776156', position: 'atf' }}, For example, the ABO blood grouping is controlled by the ABO gene, which has six common alleles. var mapping_topslot_b = googletag.sizeMapping().addSize([746, 0], [[728, 90]]).addSize([0, 0], []).build(); { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_btmslot' }}]}, }; { bidder: 'ix', params: { siteId: '555365', size: [120, 600] }}, googletag.pubads().setTargeting("sfr", "cdo_dict_english"); Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_Billboard' }}, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_btmslot' }}, 'max': 8, 'increment': 0.05, googletag.pubads().setTargeting("cdo_c", ["science_geographic_locales"]); storage: { Alleles can come in di… { bidder: 'sovrn', params: { tagid: '446382' }}, dfpSlots['houseslot_a'] = googletag.defineSlot('/2863368/houseslot', [300, 250], 'ad_houseslot_a').defineSizeMapping(mapping_houseslot_a).setTargeting('sri', '0').setTargeting('vp', 'mid').setTargeting('hp', 'right').setCategoryExclusion('house').addService(googletag.pubads()); 等位基因，對偶基因（位於一對同源染色體的相同位置上控制某一性狀的不同形態的基因）…, 等位基因，对偶基因（位于一对同源染色体的相同位置上控制某一性状的不同形态的基因）…, bir hücrenin kromozomunda aynı konumda bulunan karakteristik özellikleri kontrol eden hücrelerin iki veya daha fazla genden birisi…. { bidder: 'sovrn', params: { tagid: '346698' }}, Mit Flexionstabellen der verschiedenen Fälle und Zeiten Aussprache und relevante Diskussionen Kostenloser Vokabeltrainer { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_topslot' }}, Such a "wild type" allele was historically regarded as leading to a dominant (overpowering - always expressed), common, and normal phenotype, in contrast to "mutant" alleles that lead to recessive, rare, and frequently deleterious phenotypes. params: { pbjs.que.push(function() { { bidder: 'ix', params: { siteId: '195467', size: [300, 250] }}, // FIXME: (temporary) - send ad requests only if PlusPopup is not shown { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_MidArticle' }}, 'pa pdd chac-sb tc-bd bw hbr-20 hbss lpt-25' : 'hdn'">. googletag.pubads().setTargeting("cdo_l", "en"); gdpr: { Principal Translations: Inglés: Español: allele n noun: Refers to person, place, thing, quality, etc. [5][6] An allele is one of two, or more, versions of the same gene at the same place on a chromosome. name: "idl_env", Spanish / Español: alelo. bids: [{ bidder: 'rubicon', params: { accountId: '17282', siteId: '162036', zoneId: '1666926', position: 'btf' }}, { bidder: 'onemobile', params: { dcn: '8a969411017171829a5c82bb4deb000b', pos: '8a9699e70178783c43f941643ca4022f' }}, { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_topslot' }}]}, { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_HDX' }}, Other disorders, such as Huntington's disease, occur when an individual inherits only one dominant allele. googletag.pubads().set("page_url", "https://dictionary.cambridge.org/dictionary/english/allele"); { bidder: 'ix', params: { siteId: '555365', size: [160, 600] }}, }, }, { bidder: 'ix', params: { siteId: '195451', size: [300, 50] }}, Any individual has one of six possible genotypes (IAIA, IAi, IBIB, IBi, IAIB, and ii) which produce one of four possible phenotypes: "Type A" (produced by IAIA homozygous and IAi heterozygous genotypes), "Type B" (produced by IBIB homozygous and IBi heterozygous genotypes), "Type AB" produced by IAIB heterozygous genotype, and "Type O" produced by ii homozygous genotype. var mapping_btmslot_a = googletag.sizeMapping().addSize([746, 0], [[300, 250], 'fluid']).addSize([0, 0], [[300, 250], [320, 50], [300, 50], 'fluid']).build(); googletag.pubads().setTargeting("cdo_tc", "resp"); Other disorders are also due to recessive alleles, but because the gene locus is located on the X chromosome, so that males have only one copy (that is, they are hemizygous), they are more frequent in males than in females. { bidder: 'openx', params: { unit: '539971080', delDomain: 'idm-d.openx.net' }}, filterSettings: { ga('send', 'pageview'); Add allele to one of your lists below, or create a new one. "noPingback": true, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_rightslot' }}, allele meaning. { bidder: 'ix', params: { siteId: '195451', size: [320, 50] }}, var mapping_rightslot = googletag.sizeMapping().addSize([746, 0], [[300, 250]]).addSize([0, 0], []).build(); }, allele significado, definición, qué es allele: 1. a gene that is found in one of two or more different forms in the same position in a chromosome…. Exemplos: el televisor, un piso. { bidder: 'appnexus', params: { placementId: '11654208' }}, googletag.pubads().disableInitialLoad(); It derives from the Greek prefix ἀλληλο-, allelo-, meaning "mutual", "reciprocal", or "each other", which itself is related to the Greek adjective ἄλλος, allos (cognate with Latin alius), meaning "other". It is now appreciated that most or all gene loci are highly polymorphic, with multiple alleles, whose frequencies vary from population to population, and that a great deal of genetic variation is hidden in the form of alleles that do not produce obvious phenotypic differences. { bidder: 'onemobile', params: { dcn: '8a969411017171829a5c82bb4deb000b', pos: '8a9694390178783c4ccf416493da026b' }}, else { bidder: 'sovrn', params: { tagid: '346693' }}, { bidder: 'appnexus', params: { placementId: '11654156' }}, { bidder: 'ix', params: { siteId: '195451', size: [320, 50] }}, params: { { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_leftslot' }}]}, { bidder: 'openx', params: { unit: '539971065', delDomain: 'idm-d.openx.net' }}, { bidder: 'onemobile', params: { dcn: '8a9690ab01717182962182bb50ce0007', pos: '8a9694390178783c4ccf4164d12a0272' }}, { bidder: 'ix', params: { siteId: '195466', size: [728, 90] }}, { bidder: 'sovrn', params: { tagid: '346693' }}, { bidder: 'ix', params: { siteId: '555365', size: [120, 600] }}, if(window.isGDPRMode()) { }); { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_leftslot' }}]}, { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_SR' }}, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_rightslot2' }}, In this video, I will show you how to say the word allele as well as what allele means. { bidder: 'appnexus', params: { placementId: '19042093' }}, { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_MidArticle' }}, googletag.cmd.push(function() { defaultGdprScope: true, 'cap': true 'min': 31, For a simple model, with two alleles; where p is the frequency of one allele and q is the frequency of the alternative allele, which necessarily sum to unity. { bidder: 'sovrn', params: { tagid: '346698' }}, { bidder: 'appnexus', params: { placementId: '11654157' }}, { bidder: 'ix', params: { siteId: '195451', size: [300, 50] }}, An allele is one of two, or more, forms of a given gene variant. It can also refer to different sequence variations for several-hundred base-pair or more region of the genome that codes for a protein. var mapping_houseslot_a = googletag.sizeMapping().addSize([963, 0], [300, 250]).addSize([0, 0], []).build(); (biology) jump to other results. For this analysis, rare alleles were combined, thereby reducing a total of 124 alleles over the six microsatellites down to 49. However, many traits defy this simple categorization and the phenotypes are modeled by co-dominance and polygenic inheritance. ga('set', 'dimension2', "entryex"); },{ The degree and pattern of dominance varies among loci. any of two or more variants of a gene that have the same relative position on homologous chromosomes and are responsible for alternative characteristics, such as smooth or wrinkled seeds in peas. iasLog("exclusion label : lcp"); var pbAdUnits = getPrebidSlots(curResolution); googletag.pubads().collapseEmptyDivs(false); In this case, the chromosomes can be paired. type: "html5", dfpSlots['topslot_b'] = googletag.defineSlot('/23202586/cdo_topslot', [[728, 90]], 'ad_topslot_b').defineSizeMapping(mapping_topslot_b).setTargeting('sri', '0').setTargeting('vp', 'top').setTargeting('hp', 'center').addService(googletag.pubads()); bids: [{ bidder: 'rubicon', params: { accountId: '17282', siteId: '162036', zoneId: '776156', position: 'atf' }}, { bidder: 'appnexus', params: { placementId: '11654174' }}, It was formerly thought that most individuals were homozygous for the "wild type" allele at most gene loci, and that any alternative "mutant" allele was found in homozygous form in a small minority of "affected" individuals, often as genetic diseases, and more frequently in heterozygous form in "carriers" for the mutant allele. } addPrebidAdUnits(pbAdUnits); Allel definition: any of two or more variants of a gene that have the same relative position on homologous... | Meaning, pronunciation, translations and examples 'max': 30, { bidder: 'criteo', params: { networkId: 7100, publisherSubId: 'cdo_rightslot2' }}, type: "html5", { bidder: 'openx', params: { unit: '539971081', delDomain: 'idm-d.openx.net' }}, { bidder: 'sovrn', params: { tagid: '346688' }}, However, sometimes, different alleles can result in different observable phenotypic traits, such as different pigmentation. ", "Genes and genetics: the language of scientific discovery", "Sequence variation at the human ABO locus", https://en.wikipedia.org/w/index.php?title=Allele&oldid=1013645323, Creative Commons Attribution-ShareAlike License, This page was last edited on 22 March 2021, at 18:36. Allel. name: "pbjs-unifiedid", { bidder: 'sovrn', params: { tagid: '705055' }}, name: "unifiedId", type: "cookie", bids: [{ bidder: 'rubicon', params: { accountId: '17282', siteId: '162036', zoneId: '776130', position: 'btf' }}, allele. Recessive genetic disorders include albinism, cystic fibrosis, galactosemia, phenylketonuria (PKU), and Tay–Sachs disease. The word "allele" is a short form of allelomorph ("other form", a word coined by British geneticists William Bateson and Edith Rebecca Saunders),[10][11] which was used in the early days of genetics to describe variant forms of a gene detected as different phenotypes. { bidder: 'sovrn', params: { tagid: '387233' }}, An allele is one of two, or more, versions of the same gene at the same place on a chromosome. Allele definition, any of several forms of a gene, usually arising through mutation, that are responsible for hereditary variation. { bidder: 'pubmatic', params: { publisherId: '158679', adSlot: 'cdo_topslot' }}]}, iasLog("criterion : cdo_dc = english"); { bidder: 'ix', params: { siteId: '195465', size: [300, 250] }}, { bidder: 'appnexus', params: { placementId: '11654156' }}, { bidder: 'onemobile', params: { dcn: '8a969411017171829a5c82bb4deb000b', pos: '8a9694390178783c4ccf4164f43a0276' }}, allele definition: 1. a gene that is found in one of two or more different forms in the same position in a chromosome…. { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_HDX' }}, ga('require', 'displayfeatures'); } else { { bidder: 'triplelift', params: { inventoryCode: 'Cambridge_SR' }}, dfpSlots['houseslot_b'] = googletag.defineSlot('/2863368/houseslot', [], 'ad_houseslot_b').defineSizeMapping(mapping_houseslot_b).setTargeting('sri', '0').setTargeting('vp', 'btm').setTargeting('hp', 'center').setCategoryExclusion('house').addService(googletag.pubads());